Hair Loss and Hair Loss Treatment

Peter H. Proctor, PhD, MD

Hair Loss ? Our program for the treatment of hair loss ( " alopecia " ) is the product of 15 years of development and screening of therapeutic agents. We offer both prescription and non-prescription scalp hair regrowth formulations useful for treatment of balding, alopecia, and hair-loss in men and women.

Our Products

Proxiphen-N for Hair Loss Treatment

Proxiphen-N is a topical formulation of many of the nonprescription hair loss treatment agents coming out of our screening program. These include various SODases, copper-binding peptides, and pyridine-N-oxide hair regrowth stimulators.

NANO Shampoo and Conditioner for Hair Loss Treatment

NANO shampoo and Conditioner contain the minoxidil-like hair regrowth stimulator NANO ( nicotinic acid N-oxide ). In addition, NANO shampoo contains an SODase-type hair growth stimulating agent. NANO Shampoo is a good adjuvant treatment for either proscription Proxiphen or Proxiphen-N.

Proxiphen ( Prescription Formulation for Hair Loss Treatment )

This contains minoxidil, as well as the prescription agents phenytoin and spironolactone ( a potent topically-effective antiandrogen ), plus several other hair-growth stimulating agents It grows significantly more hair on more people than any other agent. Because it contains prescription agents, Proxiphen can only be dispensed on a physician's diagnosis of hair loss. Read the special instructions on how to obtain prescription Proxiphen without coming to Houston.

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hair In the US, you can only get it if you are a dog or a horse, but it is an approved drug in most of the hair rest of the world.

Because of their effectiveness in the general treatment of inflammatory and degenerative diseases, researchers are constantly looking at SODases and related agents in experimental animal models of disease. In the course of such studies, researchers repeatedly rediscover that SODases stimulate hair growth and decrease hair loss.

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Balding

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Hair Loss

Superoxide dismutases are enzymes which destroy superoxide free radical ( O2- ), an important biological mediator. In many systems ( e.g., blood vessel dialatation, blood clotting, etc.), superoxide opposes the action of another ubiquitous messenger substance, nitric oxide. Nitric oxide is probably one "natural" form of the hair-growth stimulating drug minoxidil and a natural modulator of hair growth. Apparently, nitric oxide tells hair to start and keep growing, superoxide tells hair to stop growing and fall out.

Also, superoxide reacts with nitric oxide to form toxic products. These may be important in mediating parts of the immune response, as well as for tissue damage in a large number of diseases. hir loss, hyr loss, hyl loss, hil loss hia loss har hal loss, hari loss, hali loss, hai loss, halr loss, ahir loss

This discovery is typically followed by a patent application. This is why there are several US and foreign patents on SODases for the treatment of hair loss. BTW, I accidentally discovered this effect of SOD in the late 1970's while doing research on diabetic rats at Bayor College of Medicine. Since I was first, I have the "prime patent". BTW, this patent took over a decade to issue.

With some exceptions, the patents listed below cover low molecular weight peptides which complex with copper or other metals to form superoxide dismutases. Again,
Unfortunately, most medical reporters, doctors, etc. don't know to look at patents, which are the first place any drug developer looks. So, a lot of stuff goes unreported and unrecognized. You heard it here how P was able to step in ). This is the first US patent so far. Priority is what counts and we've sure got that.

TEMPO and related compounds are SODases, among other things. Researchers at The National Cancer Institute report that TEMPO and TEMPOL, also covered in this patent, prevent hair loss in radiation treatment. No, neither compond is in any of our formulas yet. However, a related compound, NANO, is in all our formulations.

6) Topical SOD for Treating Hair Loss,

Proctor, P. US Pat# 5,40,876

Abstract: SOD for treating hair loss is disclosed. The SOD has utility in a topical pharmaceutical formulation for the cosmetic treatment of hair loss and the cosmetic stimulation of hair regrowth. The SOD comprises copper salicylate, copper aspirinate, indomethacin copper, or a metal complex of an aminoacid and a transition metal.

This is the prime patent in this area. Even incorporates Trichomin, etc.

7) The most recent patent from the holder of the "Trichomin" patent.

Tissue Protective and Regenerative Compositions US Pat # 5,382,431 Issue Date: 1-17-95 Pickart; Loren R. Bellevue WA

8) I have been granted several more additional US patents for Nitrone and niroxide spin traps and spin labels. As of this date (oct., '97 ) thye have not issued, but should do so in the next several months. These agents are usful for hair lossalopecia a lot of other degenerative conditions besides balding, BTW. Hiar loss treatment skin care facial skin care antiaging generatim nervis prosunt pedibusve aut coxendicibus, Hair Loss aliae luxatis fractisve, inaniunt alvos, sanant vulnera, hair loss cerovive is the trademark of astrazeneca for nxy-059 nitrone nitroxide nitroxides conductive renovis organic polymers semiconductors dismutase free radical

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